在早产婴儿中出现再综合征的发生率和危险因素
Suzan S Asfour1, Belal Alshaikh2, Maya Mathew1
1Clinical Pharmacy Department, Pharmaceutical Care Services, King Saud Medical City, Riyadh 12746, Saudi Arabia.
Nutrients
|August 10, 2024
概括
再养综合征 (RFS) 影响38%的早产婴儿,男性性别和腹腔内出血 (IVH) 的风险增加. 较低的酸摄入量与这一关键新生儿群体的RFS发病率降低有关.
科学领域:
- 新生儿科学 新生儿科学
- 儿科重症监护中心儿童重症监护中心
- 营养科学 营养科学
背景情况:
- 重新养综合征 (RFS) 对脆弱的早产婴儿构成重大风险.
- 早期的营养支持对生长至关重要,但可以导致代谢并发症.
- 在极度早产婴儿中确定RFS的风险因素对于主动管理至关重要.
研究的目的:
- 为了确定早产婴儿 (≤32周妊娠年龄) 在生命的第一个星期内的再养综合征 (RFS) 的发生率.
- 确定与该人群中RFS发展相关的关键风险因素.
- 为临床实践提供有关新生儿重症监护室 (NICU) 中RFS预防和管理的信息.
主要方法:
- 对760名早产婴儿 (妊娠年龄≤32周,出生体重<1500克) 的回顾性分析,这些婴儿被录取到III级NICU.
- 在2015年1月至2024年4月期间收集的关于接受亲肠道营养的婴儿的数据.
- 修改后的逻辑-波松回归与通用线性模型和强大的差异估计用于分析风险因素.
主要成果:
- 共有289名婴儿 (38%) 患有RFS.
- 男性性别 (aRR 1.31) 和腹腔内出血 (IVH) (aRR 1.71) 与增加RFS风险显著相关.
- 更高的酸摄入量与显著降低RFS风险相关 (aRR为0.67).
结论:
- 孕期≤32周的早产婴儿表现出相当大的RFS发病率.
- 男性性别,IVH和低酸水平是RFS发展的重要危险因素.
- 进一步研究精细的诊断标准和针对早产新生儿RFS的有针对性的干预措施是有必要的.
相关概念视频
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
95
Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
95
Enteral Nutrition I: Orogastric and Nasogastric Feeding
227
Enteral nutrition delivers nutrients directly to the stomach or small intestine through a tube. This method is appropriate for patients who cannot eat but still have a functioning digestive system. It is also beneficial for individuals with swallowing difficulties, anorexia, malabsorption, or those who have undergone gastrointestinal (GI) surgery.
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
227
Pathophysiology of Diabetes
911
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
911
Anorexia Nervosa
53
Anorexia nervosa is a complex and severe eating disorder characterized by an intense fear of weight gain, an unrelenting pursuit of thinness, and a distorted body image. It often leads to dangerously low body weight relative to an individual's age and height. This disorder is marked by significant physical and psychological consequences, making it one of the most life-threatening psychiatric illnesses.
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
53
Relative Risk
129
Relative risk (RR) is a statistical measure commonly used in epidemiology to compare the likelihood of a particular event occurring between two groups. This metric is important for evaluating the relationship between exposure to a specific risk factor and the probability of a particular outcome. It plays a crucial role in medical research, public health studies, and risk assessment. Relative risk quantifies how much more (or less) likely an event is to occur in an exposed group compared to an...
129
Factors Affecting the Risk of Infection
11.5K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
11.5K


