系统性红斑狼患者的听觉血管功能障碍:系统性审查
Jiann-Jy Chen1,2, Chih-Wei Hsu3, Yen-Wen Chen1
1Prospect Clinic for Otorhinolaryngology & Neurology, Kaohsiung 81166, Taiwan.
Diagnostics (Basel, Switzerland)
|August 10, 2024
概括
系统性红斑狼 (SLE) 可能导致未被确诊的听觉静脉功能障碍. 早期识别和类固醇治疗可以扭转SLE患者的听力和平衡问题.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 类风湿病学 类风湿病学
- 神经科学是一个神经科学.
背景情况:
- 系统性红斑狼 (SLE) 中的听觉静脉功能障碍经常被低估.
- SLE可以影响听觉和前庭系统,提出的机制包括免疫反应和药物耳毒性.
研究的目的:
- 系统地审查有关SLE患者听觉静脉功能障碍的证据.
- 提出一种类固醇治疗方案,用于管理与SLE相关的听觉静脉功能障碍.
主要方法:
- 在PubMed,Embase,ClinicalKey,Web of Science和ScienceDirect的系统文献搜索.
- 使用纽卡斯尔-太华尺度对包含的产品进行质量评估.
主要成果:
- 目前用于SLE相关的听觉静脉功能障碍的诊断测试缺乏特异性和敏感性.
- 关于治疗疗效的证据有限,没有确立的共识.
结论:
- 在SLE中,听觉静脉功能障碍在及时诊断和适当治疗的情况下可能是可逆的.
- 修改后的类固醇治疗方案被提议作为潜在的管理策略.
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