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血清乳酸脱酶的变化作为头状细胞癌患者的预后因素,这些患者接受了免疫检查点抑制剂的治疗

Woo Hee Lee1, Yukinori Takenaka1, Kiyohito Hosokawa1

  • 1Department of Otorhinolaryngology-Head and Neck Surgery, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.

Acta oto-laryngologica
|August 10, 2024
PubMed
概括

在免疫检查点抑制剂 (ICI) 治疗期间乳酸脱酶 (LDH) 水平的变化可以预测头癌患者的治疗结果. 监测这种变化 (ΔLDH) 有助于确定预后,并指导正在进行的ICI治疗决策.

关键词:
乳酸脱酶的使用方法头部和部状细胞癌瘤免疫检查点抑制剂 免疫检查点抑制剂转移的固体癌症 转移的固体癌症预后标志物是一个预后标志物.

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.