多功能且高效的哺乳动物基因组编辑使用Desulfovibrio vulgaris的I-C型CRISPR系统

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Updated: Jun 17, 2025

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Published on: May 25, 2018

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Pan Li1,2,3, Dingcai Dong1, Fei Gao1

  • 1State Key Laboratory of Animal Biotech Breeding, College of Biological Sciences, National Engineering Laboratory for Animal Breeding, Frontiers Science Center for Molecular Design Breeding, China Agricultural University, Beijing, 100193, China.

Science China. Life sciences
|August 10, 2024
PubMed
概括

来自Desulfovibrio vulgaris (Dvu) 的新型CRISPR-Cas系统可以实现精确的哺乳动物基因组编辑. 这种类型I-C系统有效地在细胞和动物中创建删除,替换和基编辑.

关键词:
德苏尔福维布里奥尔加里斯 (Desulfovibrio vulgaris) 是一种常见的Dvu 类型 I-C 编辑器基础编辑 基础编辑定义删除删除的定义.大片段的替换大片段的替换第一种类型的CRISPR系统.

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