长期太极拳治疗对精神分裂症患者的免疫炎症途径的影响,与抗精神病药物稳定
Wei Yang1, Hui-Jing Chen1, Jin Song1
1Department of Psychiatric Rehabilitation Ward 2, Wuhan Mental Health Center, Wuhan, China.
Molecular neurobiology
|August 10, 2024
概括
太极拳治疗改善了患者的精神分裂症症状和认知功能. 这种补充治疗减少了TNF-α和IL-5等炎症标志物,这表明它在免疫调节中的作用.
科学领域:
- 精神病学和免疫学 精神病学和免疫学
- 神经科学是一个神经科学.
- 补充和替代医学 补充和替代医学
背景情况:
- 精神分裂症是一种慢性精神障碍,具有显著的认知和免疫系统失调.
- 目前针对精神分裂症的治疗方法提供了部分症状缓解,并且通常对认知缺陷和炎症过程的影响有限.
研究的目的:
- 为了研究长时间的太极拳治疗作为精神分裂症的补充治疗的效果.
- 评估太极拳对精神分裂症患者认知功能和免疫-炎症通路的影响.
主要方法:
- 一项为期24周的随机对照试验,涉及90名精神分裂症患者,被分配到太极拳治疗 (TT) 或常规治疗 (RT) 组.
- 血细胞因子水平 (IL-10,IFN-γ,IL-5,GM-CSF,TNF-α,IL-13,IL-4,IL-2,IL-12) 的分析以及临床评估 (CGI,WHOQUOL-BREF,SOFS,PSS,BPRS,SAPS,SANS,RBANS) 的分析.
主要成果:
- 与常规治疗组相比,太极拳治疗组显示TNF-α和IL-5水平显著降低.
- 太极拳组的患者在SAPS,SANS,PSS,SOFS和RBANS的得分中表现出更大的改善.
- 在太极拳组中观察到血TNF-α水平和SANS/SPFS得分之间的正相关性.
结论:
- 太极拳治疗,作为标准护理的辅助,可以有效地改善精神分裂症患者的临床症状和认知功能.
- 太极拳的治疗效益可能通过其免疫调节作用来调节,特别是通过减少特定的促炎细胞因子.
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