患有急性损伤的患者的VExUS分数和死亡率:来自多学科前性研究的发现
Mehmet Ali Aslaner1, Özant Helvacı2, Korbin Haycock3
1Department of Emergency Medicine, Gazi University Faculty of Medicine, Ankara. maliaslaner@gazi.edu.tr.
Medical ultrasonography
|August 10, 2024
概括
静脉过量超声波 (VExUS) 评分不能预测急性损伤 (AKI) 患者的总体死亡率. 然而,较高的VExUS等级表明特定亚组的生存率较低,包括心脏病患者和AKI等级1患者.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 临界护理医学 临界护理医学
- 诊断成像 诊断成像 诊断成像
背景情况:
- 急性损伤 (AKI) 是一种常见的临床综合征,具有显著的发病率和死亡率.
- 预测AKI患者死亡率的生物标志物对于及时干预和改善患者结果至关重要.
- 静脉过量超声波 (VExUS) 评分的实用性,这是液体过载的测量,在预测AKI死亡率方面仍然不清楚.
研究的目的:
- 调查AKI患者VExUS得分和6个月死亡率之间的关联.
- 为了确定这个患者队列中死亡率的预测因素.
主要方法:
- 对246名进入第三级护理急诊室的AKI患者进行了后期分析.
- 进行了静脉超声波评估,以计算VExUS得分.
- 考克斯回归分析被用来确定死亡率预测因素.
主要成果:
- 总体VExUS评分没有显著预测一般AKI队列的6个月死亡率.
- 在子组分析中,VExUS等级2-3与心脏脏子组 (HR:3.98) 和AKI等级1 (HR:4.07) 的患者的生存率下降有关.
- 死亡率的预测因素包括晚年,恶性瘤,低缩血压,脉升高和乳酸盐水平升高.
结论:
- 维克苏斯评分并不是在向急诊室介绍的AKI患者的一般人群中预测6个月死亡率的可靠指标.
- 较高的VExUS分数 (2-3级) 可能表明特定AKI亚组的存活率较低,即心脏脏病患者和AKI1级患者.
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