长期暴露于环境甲和呼吸道死亡风险之间的关联:中国的一项全国性研究
Siwen Yu1, Qijiong Zhu1, Min Yu2
1Department of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou 510632, China; China Greater Bay Area Research Center of Environmental Health, School of Medicine, Jinan University, Guangzhou 510632, China; Key Laboratory of Viral Pathogenesis & Infection Prevention and Control, Jinan University, Ministry of Education, Guangzhou 510632, China.
Ecotoxicology and environmental safety
|August 10, 2024
概括
环境甲 (HCHO) 水平的上升与中国呼吸道死亡率的增加有关. 这项研究强调HCHO是导致呼吸道死亡的重要原因,强调需要控制污染.
科学领域:
- 环境健康 环境健康
- 流行病学 流行病学
- 毒理学 毒理学 毒理学
背景情况:
- 全球环境甲 (HCHO) 度正在上升,但其对健康的影响仍未得到充分研究.
- 关于长期HCHO暴露与呼吸系统健康结果之间的关联,数据有限.
研究的目的:
- 评估长期环境中HCHO暴露与中国呼吸道死亡风险之间的联系.
- 量化可归因于HCHO暴露的死亡负担.
主要方法:
- 利用来自中国466个县/区 (2013-2016) 的呼吸道死亡和HCHO水平的数据.
- 采用差异差异方法与通用线性混合效应回归.
- 计算了可归因分数 (AF) 来确定HCHO对呼吸道死亡率的贡献.
主要成果:
- 对560,929例呼吸道死亡病例的分析显示,HCHO与死亡率之间存在显著的关联.
- HCHO的1.00×10^15分子.cm^-2增加与呼吸道死亡风险的1.61%增加相关.
- 每年,HCHO占呼吸道死亡人数的12.16%,总计约125,422人死亡,在老年人,寒冷季节,城市地区和COPD患者中观察到更高的风险.
结论:
- 长期暴露于环境HCHO显著增加呼吸道死亡的风险.
- 在中国,HCHO污染造成大量死亡,需要采取紧急控制措施.
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