不同季度的产前抑郁症状与产周结局之间的关联:中国的一项前性多中心队列研究
Fangyue Zhou1, Jiaying Wu1, Lulu Wang2
1Shanghai Key Laboratory of Embryo Original Diseases, The International Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Asian journal of psychiatry
|August 10, 2024
概括
怀孕期间的孕产妇抑郁症,即使在头三个月,也与婴儿的大小和生长问题有关. 对产前抑郁症的早期查对于更好的产周结果至关重要.
科学领域:
- 围产期健康 围产期健康
- 母亲心理健康 母亲心理健康
- 婴儿发育婴儿的发展.
背景情况:
- 母亲产前抑郁症可能会对围产期的结果产生负面影响,但现有的研究是不一致的,通常忽略了早期怀孕.
- 之前的研究主要集中在第二或第三季度的抑郁症状上.
研究的目的:
- 调查孕期所有三个月的母亲抑郁症状与婴儿生长参数之间的关联.
- 为了确定怀孕期间抑郁症状的时间是否会影响特定的婴儿结果.
主要方法:
- 使用中加健康生活轨迹倡议数据进行的前性队列研究.
- 爱丁堡产后抑郁量表 (EPDS) 选了第一,第二和第三个三个月的抑郁症状.
- 婴儿成长指标在第一年被测量;使用后勤回归,斯皮尔曼相关性和通用估计方程 (GEE) 模型.
主要成果:
- 在第一个或第二个三个月内,较高的EPDS得分与宏观症的风险增加有关.
- 第三个三个月的EPDS得分升高与早产风险更高,并且对于妊娠年龄来说小.
- 第三个三个月的抑郁症状预测了婴儿甲下皮厚度的增加.
结论:
- 怀孕期间母亲的抑郁症状与婴儿体重和生长参数的差异关联.
- 这些发现强调了查抑郁症在所有妊娠季度 (包括第一季度) 的重要性.
- 早期识别和管理产前抑郁症对于优化婴儿健康结果至关重要.
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