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Updated: Jun 17, 2025

SUMO-Binding Entities SUBEs as Tools for the Enrichment, Isolation, Identification, and Characterization of the SUMO Proteome in Liver Cancer
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USP24通过duebiquitinating和稳定TRAF2促进肝细胞癌瘤发生

Nana Zhou1, Chaoqin Guo1, Xiangyu Li2

  • 1School of Basic Medical Sciences and Forensic Medicine, Hangzhou Medical College, Hangzhou, 310053, China.

Biochemical pharmacology
|August 10, 2024
PubMed
概括

乌比基特异性酶24 (USP24) 通过稳定TRAF2和激活AKT/NF-κB信号,促进肝细胞癌 (HCC) 的生长. 抑制USP24可能会增强HCC免疫疗法的疗效.

关键词:
肝细胞癌是肝细胞癌.免疫逃逸是一种免疫逃避.在PD-L1中.在TRAF2中,美国24美元

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