Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

4.9K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
4.9K
Attribution Theory00:56

Attribution Theory

12.9K
Behavior is a product of both the situation (e.g., cultural influences, social roles, and the presence of bystanders) and of the person (e.g., personality characteristics). Subfields of psychology tend to focus on one influence or behavior over others. Situationism is the view that our behavior and actions are determined by our immediate environment and surroundings. In contrast, dispositionism holds that our behavior is determined by internal factors (Heider, 1958).
12.9K
Combined Effects of Drugs: Synergism01:27

Combined Effects of Drugs: Synergism

3.8K
Synergism is a useful mechanism where combining two or more drugs is more effective than each constituent used alone. Such combinations are also called supra-additive interactions. The drugs collectively enhance the final therapeutic effect by acting on different targets. Another advantage is that the low dose of each constituent drug is sufficient to achieve the desired effect. This helps reduce the duration of therapy and lower the adverse effects of these drugs.
Such synergistic combinations...
3.8K
Combined Effects of Drugs: Antagonism01:30

Combined Effects of Drugs: Antagonism

8.4K
The combined effects of drugs can result in various interactions, of which an important type is antagonism. Antagonism is a mechanism where one drug inhibits or counteracts the effects of another drug. Antagonism can occur through various means, including receptor binding, allosteric modulation, functional interaction, chemical reactions, and pharmacokinetic processes.
The most common type is receptor antagonism, where one drug acts as an antagonist to block the effects of another drug by...
8.4K
Agonism and Antagonism: Quantification01:14

Agonism and Antagonism: Quantification

335
When drugs are administered, they can elicit either an agonist or antagonist effect on the body. Agonism occurs when a drug activates a specific receptor, triggering a biological response. On the other hand, antagonism happens when a drug binds to the same receptors but blocks their activation, thereby preventing a biological response.
To quantify these effects, researchers use a dose-response curve, which provides valuable information about the potency and efficacy of a drug. Potency refers to...
335
Guidelines for Writing Outcome01:11

Guidelines for Writing Outcome

2.7K
When developing expected outcomes for a patient care plan, the nurse should adhere to the following recommendations:
Patient outcomes reflect the patient's response to the goal rather than what the nurse aims to achieve. Terminology should be observable and measurable to avoid the reader's interpretation. The desired outcome should be realistic and achievable in the designated care timeframe. Expected outcomes should align with adjunctive therapies. The outcome should enhance care...
2.7K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Evaluating the socioeconomic value of adult respiratory immunization in Spain: a benefit-cost analysis.

Expert review of vaccines·2026
Same author

Evaluating the societal value of adult respiratory vaccination in Sweden: a benefit-cost analysis.

Expert review of vaccines·2026
Same author

Readiness to Consider and Adopt Genetic and Genomic Tests in Canada-An Update to the State of Readiness Report.

Current oncology (Toronto, Ont.)·2026
Same author

Applying Health Economics and Outcomes Research Methods in Value-Based Healthcare Implementation: An ISPOR Special Task Force Report.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research·2026
Same author

A cost-benefit analysis of adult immunization programs across ten countries: Modeling the socioeconomic value of immunization for older populations compared to no vaccination.

Human vaccines & immunotherapeutics·2025
Same author

Two-Stage Estimation of Overall Survival in the Phase 3 CheckMate 9ER Trial, Adjusting for the Impact of Subsequent Therapy.

Oncology and therapy·2025

相关实验视频

Updated: Jun 17, 2025

Combining Behavioral Endocrinology and Experimental Economics: Testosterone and Social Decision Making
11:51

Combining Behavioral Endocrinology and Experimental Economics: Testosterone and Social Decision Making

Published on: March 2, 2011

15.1K

关于基于结果的综合疗法价值赋值框架的建议

Lotte Steuten1, Mickael Lothgren2, Andrew Bruce3

  • 1Office of Health Economics, London, England, UK.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research
|August 10, 2024
PubMed
概括

一个新的价值归因解决方案基于相对价值定价组合治疗组件,解决竞争法和定价挑战. 这种通用和对称的方法为复杂的药物组合提供了一个完整的估值框架.

关键词:
组合疗法 组合疗法 组合疗法卫生政策 卫生政策卫生技术评估 卫生技术评估瘤学 在瘤学方面.价值归因价值归因

更多相关视频

Measuring the Subjective Value of Risky and Ambiguous Options using Experimental Economics and Functional MRI Methods
13:04

Measuring the Subjective Value of Risky and Ambiguous Options using Experimental Economics and Functional MRI Methods

Published on: September 19, 2012

12.1K
Pavlovian Conditioned Approach Training in Rats
06:57

Pavlovian Conditioned Approach Training in Rats

Published on: February 4, 2016

10.9K

相关实验视频

Last Updated: Jun 17, 2025

Combining Behavioral Endocrinology and Experimental Economics: Testosterone and Social Decision Making
11:51

Combining Behavioral Endocrinology and Experimental Economics: Testosterone and Social Decision Making

Published on: March 2, 2011

15.1K
Measuring the Subjective Value of Risky and Ambiguous Options using Experimental Economics and Functional MRI Methods
13:04

Measuring the Subjective Value of Risky and Ambiguous Options using Experimental Economics and Functional MRI Methods

Published on: September 19, 2012

12.1K
Pavlovian Conditioned Approach Training in Rats
06:57

Pavlovian Conditioned Approach Training in Rats

Published on: February 4, 2016

10.9K

科学领域:

  • 卫生经济学 卫生经济学
  • 制药价格的制定 制药价格的制定
  • 卫生政策 卫生政策

背景情况:

  • 组合疗法的估值存在挑战,原因是竞争法,价格差异和组件价值归因.
  • 现有的方法很难在组合治疗中公平地定价单个组件.

研究的目的:

  • 为组合疗法提出一种新的价值赋值解决方案.
  • 根据其相对贡献,为所有组合组件提供公平的定价.

主要方法:

  • 开发了一种通用,对称和中性价值赋值解决方案.
  • 确保解决方案完全赋予组件之间的组合值.
  • 将该方法应用于任何大小的组合,并与现有方法进行比较.

主要成果:

  • 提出的解决方案的结果落在两个其他方法的结果之间,整合了每个方法的元素.
  • 价值赋值比率随着增值率的变化而调整,以反映增量价值的影响.

结论:

  • 拟议的解决方案为组合疗法评估提供了普遍适用性和成分中立性.
  • 需要进一步的研究来解决实施挑战,包括部分信息和假设放松.