关于阿坎萨摩巴角质炎发病率的观点:系统性审查和元分析
Francesco Aiello1, Gabriele Gallo Afflitto2, Francesca Ceccarelli1
1Ophthalmology Unit, Department of Experimental Medicine, Università di Roma "Tor Vergata," Rome, Italy.
Ophthalmology
|August 10, 2024
概括
阿坎萨摩巴角膜炎 (AK) 是一种罕见的传染性角膜炎的原因,在全球范围内发病率很低. 这项研究发现,在各大洲的AK发病率中没有显著差异.
科学领域:
- 眼科医生 眼科 眼科
- 传染性疾病 传染性疾病
- 微生物学 微生物学
背景情况:
- 阿坎萨摩巴角膜炎 (Acanthamoeba keratitis,简称AK) 是一种危及视力的传染性角膜炎.
- 缺乏对AK发病率的全面评估.
- 了解AK发病率对于公共卫生和临床管理至关重要.
研究的目的:
- 提供关于阿坎萨摩巴角膜炎 (AK) 全球发病率的概述.
- 分析趋势并预测未来的AK病例数量.
- 为了比较不同地理区域的AK发病率.
主要方法:
- 计算的年度中心发病率 (ACI) 的AK.
- 确定了AK与非病毒性微生物角质炎 (MK) 和一般人群的比例.
- 联合国人口前景用于未来的预测.
主要成果:
- 包括105篇文章 (1987-2022年),分析了91,951只眼睛 (5,660只眼睛有AK).
- 中位数ACI为1.9 AK眼睛/中心/年;没有显著的大陆差异.
- 据估计,每百万人口中AK的发病率为2.34,预计到2053年将增加18.5%.
结论:
- 阿坎萨摩巴角膜炎是一种相对较少发生的疾病.
- 没有观察到AK发病率的显著地理差异.
- 预计的增加凸显了持续监测和预防工作的必要性.
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