酷刑暴露调节认知控制和注意力神经网络连接在去/不去任务期间
Belinda J Liddell1, Pritha Das2, Gin S Malhi3
1School of Psychological Science, University of Newcastle, Newcastle, New South Wales, Australia; School of Psychology, UNSW Sydney, Sydney, New South Wales, Australia.
Biological psychiatry. Cognitive neuroscience and neuroimaging
|August 10, 2024
概括
酷刑幸存者显示大脑网络连接性降低,特别是影响认知控制和注意力. 这可能与创伤后应激失调症症状有关,这表明认知干预可以帮助缓解痛苦.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 认知心理学 认知心理学
背景情况:
- 酷刑创伤涉及有意的,无法控制的行为.
- 对认知控制大脑机制的长期影响在很大程度上是未知的.
研究的目的:
- 调查酷刑暴露对认知控制网络的长期影响.
- 检查网络连接和创伤后应激障碍 (PTSD) 症状之间的关系.
主要方法:
- 在Go/NoGo响应抑制任务中使用功能磁共振成像 (fMRI).
- 在33名酷刑幸存者 (TSs) 和44名非TSs中使用独立组件分析分析了大脑网络连接.
- 对人口和心理共变量进行控制,并通过网络连接探索调节.
主要成果:
- 在后置默认模式和听觉电机网络中,TSs的连接性下降.
- 在TS中,dorsomedial前端和背部注意网络之间发现了减少的连接性.
- 没有观察到行为差异,但连接性缓解了酷刑暴露和创伤后应激障碍症症状之间的联系.
结论:
- 在酷刑幸存者中,反应抑制,注意力和运动网络的联系较少.
- 这种减少的连接性可能与创伤后应激障碍症症状有关.
- 针对认知控制过程可能是缓解酷刑相关创伤后症状的有希望的途径.
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