自杀和痴呆症:一个系统的审查和流行率和风险因素的元分析
Roopal Desai1, Anastasia Tsipa1, Caroline Fearn1
1ADAPT Lab, Clinical, Educational and Health Psychology Department, University College London, London, UK.
Ageing research reviews
|August 10, 2024
概括
痴呆症患者面临更高的自杀思想和行动的风险. 针对性心理健康支持和自杀预防策略对于痴呆症护理至关重要,考虑到年龄,性别和症状严重程度.
科学领域:
- 神经科学是一个神经科学.
- 老年学是一门学科.
- 公共卫生 公共卫生
- 精神病学是一个精神病学.
背景情况:
- 痴呆症是一个日益增长的全球健康挑战,影响着越来越多的老年人群.
- 患有痴呆症 (PwD) 的人对自杀倾向的脆弱性增加.
- 与PWD中自杀相关的患病率和危险因素仍未得到充分研究.
研究的目的:
- 系统地审查和确定痴呆症患者中自杀念头,自杀企图和自杀死亡的普遍性.
- 确定导致痴呆症患者自杀的关键风险因素.
主要方法:
- 从创立到2023年7月,在五个数据库中进行了全面的文献搜索.
- 包括同行评审研究报告的流行率,风险因素,或关于自杀结果的定量数据在pwd.
- 采用随机效应模型,从54项纳入研究中合成聚合的流行率和效应大小.
主要成果:
- 在PWD中,自杀念头的点患病率为10%,自杀企图的2年和10年期间患病率分别为0.8%和8.7%.
- 自杀死亡的发生率为0.1%. 痴呆症诊断增加了自杀念头的风险 (OR=1.62),但没有自杀企图或自杀死亡.
- 中度痴呆症严重程度,年龄较小,男性与自杀念头,自杀企图和/或自杀死亡风险增加有关.
结论:
- 这份综述强调了痴呆症患者中自杀念头和自杀企图的显著流行率.
- 痴呆症护理需要综合心理健康支持和强有力的自杀预防策略.
- 干预措施应个性化,应对与年龄,痴呆症严重程度和性别相关的特定风险.
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