化在内动脉狭窄的患病率和临床影响:一项回顾性研究
Fengli Fu1, Xiaoli Liu2,3, Rui Zhang4
1Radiology Department, Zhejiang Hospital, Hangzhou, 310030, China.
BMC neurology
|August 10, 2024
概括
内动脉狭窄中的斑块化是常见的,特别是在老年人中. 阳性边缘标志是未来缺血事件的重要预测指标.
科学领域:
- 心血管成像和干预方法
- 脑血管疾病研究研究
- 动脉样硬化和斑块生物学
背景情况:
- 在先进的动脉瘤斑块中经常观察到化,但其临床含义尚未完全理解.
- 内动脉狭窄是缺血性中风的主要危险因素.
- 评估化在动脉疾病中的作用对于风险分层至关重要.
研究的目的:
- 为了确定中度至重度内动脉狭窄的斑块化的患病率.
- 为了研究各种化特征与ipsilateral缺血事件之间的关联.
- 为了确定预测脑血管事件的特定化模式.
主要方法:
- 对178名患有≥50%近壁内动脉狭窄症的患者进行了回顾性分析.
- 评估斑块化特征,包括厚度,位置,类型,范围,体积和分数,使用多探测器计算机断层扫描.
- 统计分析以将化特征与ipsilateral脑血管事件相关联.
主要成果:
- 在89.29%的狭窄动脉中存在斑块化,并且随着年龄的增长而增加.
- 阳性边缘标志和大量化与缺血事件有显著的关联.
- 阳性边缘标志被确定为ipsilateral缺血事件的独立预测因素 (OR=2.795,p=0.019).
结论:
- 斑块化在内动脉狭窄中非常普遍,其存在随着年龄的增长而增加.
- 特定的化特征,特别是正边形标志,与增加侧性缺血事件的风险有关.
- 阳性边缘标志作为一个关键的高风险指标,用于未来的缺血事件在患有动脉狭窄的患者.
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