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美国成年人中饮食中的活微生物摄入量与过度活跃的膀之间的关系:NHANES 2007-2018年的横截面研究
Yuan-Zhuo Du1,2, Hong-Ji Hu1,2, Qian-Xi Dong1,2
1Department of Urology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330000, Jiangxi Province, China.
Journal of health, population, and nutrition
|August 10, 2024
概括
更高的饮食活微生物摄入量与过度活跃膀 (OAB) 的风险降低有关. 这表明活跃的微生物群可能在预防OAB中发挥作用,并可以为饮食建议提供信息.
科学领域:
- 微生物组研究的研究.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 营养科学 营养科学
背景情况:
- 过度活动膀 (OAB) 背后的机制尚未完全理解.
- 饮食因素,包括活微生物,可能会影响膀功能.
- 调查饮食活性微生物群和OAB之间的联系对于了解预防策略至关重要.
研究的目的:
- 检查饮食中食用活微生物与过度活性膀 (OAB) 发生率之间的关联.
- 探索不同水平的饮食活性微生物群摄入量与OAB流行率之间的关系.
主要方法:
- 一项使用2007-2018年国家健康和营养检查调查 (NHANES) 数据进行的横截面研究.
- 参与者 (n=16,795) 被分为低,中,高饮食活微生物摄入组.
- 使用权重后勤回归,限制立方线 (RCS) 和子组分析来评估OAB-微生物群关系.
主要成果:
- 与低和中等摄入量相比,高饮食活微生物摄入量与OAB的发病率降低有关.
- 摄入量较高的参与者在对共变量进行调整后,OAB的几率明显较低 (OR:0.84,95% CI:0.71-0.99,p=0.03).
- RCS分析显示,高饮食活性微生物群摄入量与OAB发生率之间存在非线性相关性.
结论:
- 摄入大量活跃微生物群的饮食可能会对过度活跃的膀 (OAB) 提供保护性益处.
- 这些发现支持将活性微生物群纳入用于预防OAB的饮食指南.
- 饮食中的活性微生物群消费与OAB的发病率降低有关.
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