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Updated: Jun 17, 2025

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
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在瘤药物开发中成功优化剂量的策略:一本实用指南

Qiqi Deng1, Lili Zhu1, Brendan Weiss2

  • 1Biostatistics and Programming, Moderna Inc., Cambridge, MA, USA.

Journal of biopharmaceutical statistics
|August 11, 2024
PubMed
概括

新的瘤药物需要新的剂量优化策略,超出传统的最大耐受剂量 (MTD) 方法. 这项研究提出了一个框架,用于改善癌症新疗法的早期临床试验中的剂量选择.

关键词:
剂量优化的优化在PK/PD中,PK/PD是最常见的.发现剂量发现剂量选择剂量选择剂量选择瘤学 在瘤学方面.这个项目是Optimus Optimus.概念证明的概念证明

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