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开发和验证口腔平流体疾病活动量表:用于全面临床评估的新型工具
Preeyaporn Somsak1,2, Pornpan Piboonratanakit1, Surawut Pongsiriwet3
1Department of Oral Medicine, Faculty of Dentistry, Chulalongkorn University, 34 Henri-Dunant Road, Wangmai, Pathumwan, Bangkok, 10330, Thailand.
Clinical oral investigations
|August 11, 2024
概括
口腔平病活动量表 (OLP-DAS) 是测量口腔平活动的新型,可靠的工具. 这种临床医生报告的结果指标对临床实践和研究有价值.
科学领域:
- 口腔医学是指口腔医学.
- 皮肤病学 皮肤病学
- 临床评估工具 临床评估工具
背景情况:
- 口腔平液 (OLP) 是一种慢性炎症状况,影响口腔粘膜.
- 准确评估OLP疾病活动对于有效管理至关重要.
- 现有的评估工具可能缺乏全面的验证或专注于疾病活动.
研究的目的:
- 开发和验证口腔平面病活动量表 (OLP-DAS).
- 确定OLP-DAS作为OLP疾病活性可靠的临床医生报告结果指标 (CROM).
主要方法:
- OLP-DAS是通过完善现有标准,并纳入专家投入和疼痛评估来开发的.
- 内容有效性由8名口腔医学专家进行评估.
- 在10名研究人员评估的17名OLP受试者中检查了可靠性和有效性,在160名受试者中评估了收有效性.
主要成果:
- OLP-DAS 显示出优异的内容有效性.
- 观察到高的inter-rater (ICC=0.93) 和intra-rater (ICC=0.96) 的可靠性.
- 在OLP-DAS得分与其他既定措施 (ODSS,OLP-IGA) 之间发现了强烈的正相关性,证实了趋同有效性.
结论:
- OLP-DAS是评估OLP疾病活性的有效和可靠的CROM.
- OLP-DAS适用于常规临床评估和OLP的研究应用.
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