"周末战士"体育活动与神经退行性疾病发生率之间的关联
Yuye Ning1, Meilin Chen2, Jiaqi An3
1Department of Cardiovascular Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an, China; Innovation Center for Neurological Disorders and Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
概括
"周末战士"的体育活动模式,每周1-2天从中等到剧烈的活动,显著降低神经退行性疾病 (NDD) 的风险. 这种模式为痴呆症和帕金森症患者提供类似于定期炼的神经保护益处.
科学领域:
- 神经学 神经学
- 公共卫生 公共卫生
- 运动科学 运动科学
背景情况:
- 目前的健康指南建议每周进行150分钟的中度至剧烈体力活动 (MVPA).
- 公司的有效性.
- 周末的战士 周末的战士
- (WW) 减少神经退行性疾病 (NDD) 风险的体力活动模式尚未得到充分证实.
研究的目的:
- 为了研究WW体育活动模式和发展NDDs的风险之间的联系.
- 为了比较与WW模式相关的NDD风险降低与定期体育活动模式.
主要方法:
- 使用英国生物银行 (2013年6月至2015年12月) 的加速计数据进行的前性队列研究.
- 参与者分为WW (≥50%或≥75%的MVPA在1-2天内),定期或不活跃的体力活动模式.
- 考克斯的比例危险模型分析了身体活动模式与NDD发生率之间的关联.
主要成果:
- 与不活动的个人相比,WW和常规模式都与所有原因痴呆症和帕金森症的风险降低有关.
- 这种WW模式显示了痴呆症的危险比率 (HR) 为0.68,帕金森症的危险比率为0.47 (在≥50%的MVPA值时).
- 即使在较高的值 (≥75% MVPA) 中,WW模式也保持了对痴呆症 (HR:0.61) 和帕金森症 (HR:0.22) 的显著风险降低.
结论:
- 建议将MVPA集中到每周1-2天 (WW模式) 与NDD的发病率较低有关.
- 这种WW模式显示,神经保护的益处与定期体力活动的分布相比较.
- 这一发现支持了公共卫生信息,即无论频率如何,积累足够的MVPA对大脑健康有益.
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