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快速和运动强大的和转移MRI具有固有的B₀校正,使用罗塞特轨迹和压缩传感感应

Sultan Z Mahmud¹, Munendra Singh¹, Peter van Zijl^1,2

¹Department of Radiology, Johns Hopkins University, Baltimore, Maryland, USA.

Magnetic resonance in medicine

|August 12, 2024

概括

这项研究引入了快速,运动强大的化学交换和转移 (CEST) 和磁化转移 (MT) 图像,使用罗塞特轨迹. 这种新方法提供了更好的图像质量和固有的B0不均性校正,加速了临床翻译.

科学领域:

磁共振成像 (MRI) 是一种磁共振成像技术.
生物医学工程生物医学工程

背景情况:

化学交换和转移 (CEST) 和磁化转移 (MT) 图像是有价值的MRI技术.
挑战包括长的获取时间,运动灵敏度和B0不均性,阻碍临床应用.

研究的目的:

开发和验证带有压缩传感的罗塞特读出轨迹,以实现快速,运动强大的CEST和MT成像.
为了在图像采集过程中实现B0不均性的固有纠正.

主要方法:

实现了一种新的脉冲序列,利用一堆具有更高k空间中心密度的迷状轨迹.
为了B0不均性估计和纠正,生成了双回声图像.
该方法在3T上对幻象和健康志愿者进行了评估,并将其与笛卡尔收购进行了比较.

主要成果:

压缩感应重建的罗塞特图像显示出优越的对比度和噪声比率,与卡特西安采集相比,读取速度更快.
准确的B0地图得到了可以忽略不计的偏差.
水和度光谱和胺质子转移信号保存良好.

结论:

罗塞特轨迹可以实现快速,运动稳定,B0校正的CEST和MT成像.
这种方法提高了图像质量和受试者舒适度,可能加速CEST-MRI的临床采用.

关键词:

在APT中,APT是APT.在B0中进行了校正.在CEST中,CEST是CEST.压缩感应传感器压缩感应罗塞特成像技术的成像

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Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...