我们是否准备好治愈中风后的认知障碍? 许多关键的先决条件可以快速轻松地实现
Olivier Godefroy1,2, Ardalan Aarabi2, Yannick Béjot3,4
1Departments of Neurology, Amiens University Hospital, France.
European stroke journal
|August 12, 2024
概括
脑卒中后认知障碍 (PSCI) 影响约50%的患者,需要更好的查和风险识别. 新的研究强调了成像标记物和康复策略,但需要更多的试验才能获得有效的治疗方法.
科学领域:
- 神经学 神经学
- 认知科学 认知科学
- 脑卒中医学 脑卒中医学
背景情况:
- 脑卒中后认知障碍 (PSCI) 是中风的常见和严重并发症.
- 尽管有影响,但PSCI仍然被诊断不足和治疗不足.
- 最近的研究重点是了解PSCI的流行病学,诊断和管理.
研究的目的:
- 审查最近的PSCI数据,以确定未满足的需求和未来的方向.
- 确定是否有新的发现可以指导减少PSCI.
- 评估解决PSCI管理的基本问题的进展情况.
主要方法:
- 自从中风单位时代以来,对PSCI研究的文献综述.
- 流行病学,风险因素,诊断方法和成像决定因素的分析.
- 评估治疗策略,包括二次预防,药物,康复和大脑刺激.
主要成果:
- PSCI 患病率可能被低估,约为50%.
- 需要改进查测试和包括冷漠在内的全面评估.
- 关键的成像决定因素包括病变位置/体积,脱节,相关的阿尔茨海默病 (AD) 和缩.
- 二次预防和症状药物对PSCI的有效性有限.
- 非侵入性脑刺激显示有前途,但需要进一步的高质量试验.
结论:
- 了解PSCI的进展为其减少铺平了道路.
- 开发敏感的查测试和远程评估工具至关重要.
- 临床和成像因素可以识别有风险的患者,并指导AD评估.
- 将认知结果纳入中风试验和对非侵入性脑刺激的验证是未来的关键步骤.
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