细菌生长和通过胺生物合成和胺介导的代谢相互作用来适应环境
Xihui Xu1, Can Li1, Weimiao Cao1
1College of Life Sciences, Nanjing Agricultural University, Nanjing 210095, China.
The ISME journal
|August 12, 2024
概括
细菌中的胺生物合成很可能是在大氧化事件期间作为适应有氧呼吸而出现的. 这种维生素辅助因子对于细菌群体的适应和进化至关重要,影响生命早期的过渡.
科学领域:
- 进化生物学 进化生物学
- 微生物生态学 微生物生态学
- 生物化学 生物化学
背景情况:
- 从无氧生活方式过渡到有氧生活方式是生命早期的关键事件.
- 推动这种转变的生物适应,特别是细菌,尚不清楚.
- 胺是新陈代谢和呼吸中的重要辅助因子,起着关键作用.
研究的目的:
- 调查胺-auxotrophic和胺-prototrophic细菌的遗传学和全球分布.
- 探索胺生物合成在细菌适应有氧环境中的作用.
- 了解胺介导的代谢相互作用对细菌群体结构和环境适应的影响.
主要方法:
- 对154,938种细菌基因组的遗传学分析,重点关注胺生物合成途径.
- 在4245个土壤样本中进行全球调查,以评估胺介导相互作用.
- 稳定同位素探测-代谢建模以分析社区中活性胺利用率.
主要成果:
- 胺合成细菌的出现与大氧化事件有很强的相关性.
- 胺介导的代谢相互作用显著影响细菌社区的组合和多样性.
- 细菌群体积极使用胺介导的相互作用来适应环境.
结论:
- 胺生物合成很可能是为了适应增加的氧气水平而演变的.
- 胺介导的代谢相互作用是细菌社区动态和适应的基础.
- 这项研究提供了对早期细菌进化和适应策略的见解.
相关概念视频
Overview of Metabolism
29.7K
Living cells constantly carry out various chemical reactions which are necessary for their proper functioning. These reactions are interlinked to one another via multiple pathways. The collection of these chemical reactions is known as metabolism.
Plant Metabolism
Sunlight, the primary source of energy in plants, is first absorbed by the chlorophyll pigments present in their leaves. Plants then use this energy to carry out photosynthesis, where water is oxidized into oxygen and carbon dioxide...
Plant Metabolism
Sunlight, the primary source of energy in plants, is first absorbed by the chlorophyll pigments present in their leaves. Plants then use this energy to carry out photosynthesis, where water is oxidized into oxygen and carbon dioxide...
29.7K
Riboswitches
8.1K
Riboswitches are non-coding mRNA domains that regulate the transcription and translation of downstream genes without the help of proteins. Riboswitches bind directly to a metabolite and can form unique stem-loop or hairpin structures in response to the amount of the metabolite present. They have two distinct regions – a metabolite-binding aptamer and an expression platform.
The aptamer has high specificity for a particular metabolite which allows riboswitches to specifically regulate...
The aptamer has high specificity for a particular metabolite which allows riboswitches to specifically regulate...
8.1K
Defense Against Bacterial Pathogens
1.4K
The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
1.4K
What is Metabolism?
113.6K
Overview
113.6K
The Roles of Bacteria and Fungi in Plant Nutrition
35.2K
Plants have the impressive ability to create their own food through photosynthesis. However, plants often require assistance from organisms in the soil to acquire the nutrients they need to function correctly. Both bacteria and fungi have evolved symbiotic relationships with plants that help the species to thrive in a wide variety of environments.
35.2K
Types of RNA
63.4K
Overview
Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in the regulation of gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
RNA...
Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in the regulation of gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
RNA...
63.4K


