甲基胺使用者的心肌病相关住院病例:地理和社会差异
Zaki Al-Yafeai1, Shafaqat Ali1, Jimmy Brown1
1Department of Medicine, Louisiana State University Health Sciences Center at Shreveport, Shreveport, Louisiana, USA.
JACC. Advances
|August 12, 2024
概括
甲基胺使用者 (CAHMA) 中与心肌病相关的住院病例在2008-2020年间升了231%. 这一增长凸显了美国性别,种族,年龄和地理区域的巨大差异.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 毒理学 毒理学 毒理学
背景情况:
- 甲基胺的使用是越来越严重的公共卫生问题.
- 在甲基胺使用者 (CAHMA) 中,心肌病相关住院病例的趋势和差异尚不清楚.
- 了解这些趋势对于有针对性的公共卫生干预至关重要.
研究的目的:
- 调查2008年至2020年CAHMA的趋势和流行情况.
- 分析这些趋势的各种人口因素,包括年龄,性别,种族和地理区域.
- 为了确定特定的人群不成比例地受到甲基胺相关心肌病的影响.
主要方法:
- 利用来自国家住院患者样本数据库的数据,涵盖2008-2020年.
- 确定了12845,919例心肌病入院病例,其中222,727例与甲基胺使用有关.
- 采用了通用线性模型来计算患病率并确定趋势,不包括同时使用物质的个人.
主要成果:
- 从2008年到2020年,CAHMA显示了231%的大幅增长 (P < 0.001).
- 在所有分析的人口群体中观察到显著的上升趋势,男性 (345%),西班牙裔 (565%) 和非西班牙裔亚洲人 (645%) 的人口显著增加.
- 西部地区的增长最明显 (530%),这表明地区差异很大.
结论:
- 在全国范围内,CAHMA显著增加,这凸显了甲基胺对心血管健康的影响日益加剧.
- 不平等是显而易见的,男性,西班牙裔和非西班牙裔亚洲人,以及西部地区的居民显示不成比例地增加.
- 这些发现突显了甲基胺相关心肌病的严重性别,种族/民族和区域差异,需要定制的公共卫生战略.
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