饮食中的和与血管和膜化的关联:ARIC研究
Yume Nohara-Shitama1, Yejin Mok1, Shoshana H Ballew1,2
1Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
JACC. Advances
|August 12, 2024
概括
中年高和摄入量并没有增加晚年血管或膜化. 这项研究没有发现或丰富的饮食与75岁以上个体的化之间的联系.
科学领域:
- 心血管健康 心血管健康
- 营养流行病学 营养流行病学
- 血管生物学 血管生物学
背景情况:
- 不一致的流行病学数据将高和的饮食与加速的血管化联系起来.
- 之前的研究经常在一个时间点评估饮食,缺乏系统的评估.
研究的目的:
- 调查中年饮食中的和摄入量与晚年冠状动脉和冠状动脉外化之间的关联.
主要方法:
- 分析了来自社区动脉样硬化风险 (ARIC) 研究的1914名参与者 (平均年龄为80.5岁).
- 饮食摄入量通过早期访问 (1987-1995) 的食物频率问卷进行评估,并以平均值计算.
- 使用来自胸部CT扫描 (2018-2019) 的Agatston得分量化化 (2018-2019).
主要成果:
- 饮食中的摄入量与冠状动脉和上升性大动脉化有相反的关联.
- 摄入的最高四分位数与冠状动脉化减少有关 (OR 0.66).
- 饮食也显示出类似但较弱的反向关联;对于其他化措施,没有发现显著的联系.
结论:
- 中年饮食和摄入量与75岁以上的个体的血管和膜化没有积极的关联.
- 研究结果不支持或丰富的饮食与血管或膜化增加之间的联系.
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