凝血病得分与ICU死亡率之间的关系:对MIMIC-IV数据库的分析
Zhijie Xie1, Suijun Zhu2, Jun Wang1
1Master of Medicine, The First People's Hospital of Linping District, Department of Neurosurgery, China.
Heliyon
|August 12, 2024
概括
凝血病得分显示,急性脑出血患者的重症监护室 (ICU) 死亡率与凝血病得分呈正相关性. 虽然它比单个措施更好,但它在预测ICU死亡率方面不如SAPSII或GCS得分那么有效.
科学领域:
- 关键护理医学 关键护理医学
- 神经学 神经学
- 血液学 血液学 血液学
背景情况:
- 凝血病评分是各种严重疾病的预后指标.
- 它在预测急性脑出血 (ICH) 患者的重症监护室 (ICU) 死亡率方面的实用性尚未评估.
研究的目的:
- 调查急性脑出血患者早期凝血病评分和ICU死亡率之间的关联.
- 与其他已建立的评分系统相比,评估凝血病评分的预测性能.
主要方法:
- 使用MIMIC-IV数据库 (v2.0) 进行回顾性队列分析.
- 使用多变量逻辑回归来检查凝血病得分与ICU死亡率之间的关联.
- 进行了子组分析,以探索其他变量的影响.
主要成果:
- 总共有3174名患者被纳入,其ICU死亡率为18.2%.
- 增加的凝血病得分与更高的ICU死亡率相关,在对混因素进行调整后.
- 凝血病得分的预测准确度 (AUC 0.601) 比SAPSII (0.745) 和综合指标 (0.752) 低,但表现优于血小板计数,INR和APTT等单个指标.
结论:
- 凝血病得分与急性脑出血患者的ICU死亡率正相关.
- 它比单个实验室测量更好地预测ICU死亡率,但比SAPSII评分或格拉斯哥昏迷量表 (GCS) 效率低.
更多相关视频
相关概念视频
Coagulation
Colloidal solids are solid particles suspended in solution. They are usually negatively charged, attracting a compact primary layer of positively charged ions, which attract more counterions to form an electrical double layer. Electrostatic repulsion between the charged double layers prevents the particles from colliding, stabilizing the colloids. These solids are often undesirable because they can contain toxins that are difficult to remove. Coagulation is a technique that helps aggregate and...
Coagulation
The coagulation phase is a critical part of the body's process to prevent blood loss following injury to blood vessels. It involves chemical reactions that form a clot to seal the injured area. The clotting process begins shortly after injury, within 15-20 seconds for severe damage and 1-2 minutes for minor injuries.
During the coagulation phase, clotting factors, or procoagulants, play a vital role in initiating and progressing the coagulation cascade. This cascade is a series of reactions...
During the coagulation phase, clotting factors, or procoagulants, play a vital role in initiating and progressing the coagulation cascade. This cascade is a series of reactions...


