成年人血压与三糖糖-葡萄糖指数 (TyG指数) 的关联:一项回顾性研究
Ghadeer S Aljuraiban1, Fahad J Alharbi2, Ali O Aljohi2
1Department of Community Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, 11362, Saudi Arabia.
甘油三糖 (TyG) 指数可以预测高血压 (BP),特别是缩BP. 这种关联在女性和肥胖个体中最强,这表明TyG是潜在的成本有效标志物.
科学领域:
- 内分泌学 在内分泌学.
- 心血管医学 心血管医学
- 代谢综合征是代谢综合征的一种.
背景情况:
- 高血压 (BP) 是一个重要的心血管疾病风险因素.
- 甘油三糖指数 (TyG) 识别了胰岛素耐药性,可以预测高血压.
- 有限的研究存在于TyG指数和BP关联.
研究的目的:
- 调查TyG指数与BP之间的关联.
- 探索TyG指数作为高血压的潜在预测指标.
主要方法:
- 对1596名沙特成年人 (≥18岁) 的医院数据的回顾性分析.
- 计算TyG指数,包括脂质标记物,心血压 (SBP),腹血压 (DBP) 和BMI.
- 跨TyG指数四分位数的统计分析和按性别和BMI分类的子组分析.
主要成果:
- 较高的TyG指数四分位数与较高的SBP显著相关 (p<0.03).
- 在TyG指数和DBP之间没有发现显著的关联.
- 在女性和肥胖个体中,SBP和TyG指数之间的关联是显著的.
结论:
- 泰格指数显示,作为高血压,特别是SBP高血压的成本有效预测标志物的潜力.
- 这种关联在特定的子组中更为明显,例如女性和肥胖者.
- 需要进一步的前性研究来验证这些发现.
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