较低的血红蛋白水平作为早产儿视网膜病变发展的危险因素
Rama K Gudu1, Swaranjika Sahoo1, Pravati Jena1
1Pediatrics, Kalinga Institute of Medical Sciences, Bhubaneswar, IND.
Cureus
|August 12, 2024
概括
在早产儿的初始血红蛋白水平较低,与患早产儿视网膜病变 (ROP) 的风险更高有关. 对这些易受伤害的新生儿来说,早期对ROP进行查至关重要.
科学领域:
- 新生儿医学 新生儿医学
- 眼科医生 眼科 眼科
- 血液学 血液学 血液学
背景情况:
- 早产视网膜病变 (ROP) 是早产婴儿视力丧失的重要原因之一.
- 早期发现和管理ROP对于预防视力障碍至关重要.
研究的目的:
- 调查初始全血细胞计 (CBC) 参数与早产新生儿中ROP发展之间的关联.
- 为了确定在新生儿期早期ROP的血液学预测因素.
主要方法:
- 在新生儿重症监护室对早产新生儿 (妊娠年龄<34周) 的回顾性队列研究.
- 分析出生后48小时内CBC参数,人口统计数据,新生儿发病率和ROP查结果.
- 多变量物流回归用于识别ROP开发的独立风险因素.
主要成果:
- 在148名早产新生儿中,有43名 (29.1%) 患有ROP.
- 独立的风险因素包括低出生体重,低血红蛋白 (Hb) 水平,呼吸困扰综合征 (RDS) 和需要输血红细胞 (PRBC).
- 在初始Hb水平为10.5-15.4g/dL和15.4-17.3g/dL的新生儿中,与Hb>17.3g/dL的新生儿相比,观察到ROP的几率更高.
结论:
- 在产后早期初始血红蛋白水平较低,与ROP发展风险增加有关.
- 有较低Hb水平的早产新生儿需要优先进行ROP查.
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