健康的睡眠模式,代谢疾病和中风风险:凯卢安队列研究
Lili Huang1, Yesong Liu2, Tingting Geng1
1Department of Nutrition and Food Hygiene, School of Public Health, Institute of Nutrition, Fudan University, Shanghai, People's Republic of China.
Nature and science of sleep
|August 12, 2024
概括
保持健康的睡眠模式与中国人中风风险降低有关. 代谢性疾病部分解释了这种有益的关联,突出了睡眠.
科学领域:
- 流行病学 流行病学
- 睡眠医学 睡眠医学
- 心血管健康 心血管健康
背景情况:
- 关于中国人健康睡眠模式与中风风险之间的关联的证据有限.
- 之前的研究表明,睡眠问题和中风发生率之间存在联系.
研究的目的:
- 为了研究健康睡眠模式和中风风险之间的关系,在中国队列.
- 为了检查代谢疾病在睡眠模式-中风关联中的调解作用.
主要方法:
- 分析了11,851名在基线没有中风的中国成年人队列.
- 健康睡眠得分是从包括失眠,白天嗜睡,打,睡眠时间 (7-8h/d) 在内的因素中得出的.
- 考克斯比例危险模型和调解分析被用来评估中风风险和代谢性疾病 (肥胖,糖尿病,高血压) 的影响.
主要成果:
- 较高的健康睡眠分数显示了剂量反应与较低中风风险的关联 (P-趋势=0.03).
- 与得分最低 (≤2) 的人相比,睡眠得分最健康的参与者 (4) 的中风调整风险比率明显较低.
- 代谢性疾病 (肥胖,糖尿病,高血压) 在健康睡眠得分和中风风险之间的关联中占21.9%.
结论:
- 坚持健康的睡眠模式与中国人中风风险降低有关.
- 健康睡眠对中风风险的有益影响部分是由代谢疾病介导的,这强调了它们的相互联系.
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