子侧面前额皮层子区域区分对视觉刺激的感知暴露
Kyoko Leaman1, Nadira Yusif Rodriguez1, Aarit Ahuja1
1Department of Neuroscience, Brown University.
bioRxiv : the preprint server for biology
|August 12, 2024
概括
侧面前额皮层 (LPFC) 的后腹部区域46 (p46v) 首选激活对不太熟悉的视觉刺激. 这一发现有助于在灵长类大脑中定位感知曝光处理.
科学领域:
- 神经科学是一个神经科学.
- 认知神经科学 认知神经科学
- 灵长类大脑研究研究
背景情况:
- 人类每天以不同程度的熟悉度处理视觉刺激.
- 视觉刺激暴露的神经相关物存在于灵长类动物侧面前额皮质 (LPFC).
- 在LPFC中负责暴露依赖反应的特定子区域仍然不清楚.
研究的目的:
- 调查46 (p46f) 区域的后底部或46 (p46v) 区域的后腹部是否表现出对较少出现的刺激的偏好激活.
- 为了确定p46v是否与新奇响应区域相邻,表现出暴露依赖的反应.
- 为了进一步定位灵长类LPFC内的感知暴露处理.
主要方法:
- 醒着的功能磁共振成像 (fMRI) 在三个雄性子身上进行.
- 子观察到视觉刺激的每日呈现频率不同.
- 对 p46f 和 p46v 的神经活动进行了比较,以应对这些刺激.
主要成果:
- 在p46v亚区域,表现出对具有较低感知暴露的刺激的偏好激活.
- 在p46f亚区域没有显示出对较少频繁呈现的刺激的显著反应.
- 这些发现定位了灵长类LPFC中p46v的暴露依赖性影响.
结论:
- p46v,而不是p46f,参与处理对视觉刺激的感知暴露.
- 结果支持p46f.的拟议序列特异性功能.
- 这项研究完善了我们对LPFC子区域专业化和感知处理的理解.
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