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Updated: Jun 17, 2025

Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter
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Published on: March 27, 2020

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SMURF1/2 是WNK1稳定性的新型调节剂

Ankita B Jaykumar1, Sakina Plumber1, Derk Binns1

  • 1Department of Pharmacology, UT Southwestern Medical Center, Dallas, USA.

bioRxiv : the preprint server for biology
|August 12, 2024
PubMed
概括

改变增长因子β (TGF-β) 信号传输对于血管修复至关重要. 这项研究揭示了蛋白质激酶WNK1如何与E3泛素酶相互作用,以控制TGF-β信号和血管生成.

关键词:
在ALK5中,ALK5是指ALK5.一个OSR1一个OSR1在SMURF1/2这就是SPAKK的意思.这就是WNK1的原因.

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