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在印度人中使用富含血小板的纤维素支架后,周周植入骨变化
Abhishek Balani1, Jaishree Tandon1, Vinay Kharsan1
1Department of Oral and Maxillofacial Surgery, New Horizon Dental College and Research Institute, Sakri, Bilaspur, Chhattisgarh, India.
Bioinformation
|August 12, 2024
概括
将草本提取物如Moringa oleifera和simvastatin添加到富含血小板的纤维素支架中,与单独使用支架相比,大大减少了牙科植入物周围的骨损失.
科学领域:
- 牙科植入物学 牙科植入物学
- 生物材料科学是生物材料的科学.
- 再生医学是一种再生医学.
背景情况:
- 牙植入物周围的骨再生对于长期成功至关重要.
- 富含血小板纤维素 (PRF) 支架用于增强骨愈合.
- 骨质促进剂,包括草本提取物,在骨组织工程中显示出潜力.
研究的目的:
- 为了比较单独使用PRF支架与与simvastatin (SIM) 或Moringa oleifera (MO) 结合使用PRF支架在减少牙植入物周围的骨损失的疗效.
- 评估草本提取物与PRF结合的骨质促进潜力.
- 评估这些组合在临床环境中对骨再生的影响.
主要方法:
- 一项临床研究涉及36名患者和36个牙科植入物,分为三个组 (每组12个植入物).
- 第1组:仅使用PRF脚手架.
- 第二组:使用simvastatin的PRF脚手架.
- 第三组:使用Moringa oleifera的PRF脚手架.
- 使用形光束计算断层扫描 (CBCT) 测量了形骨变化.
主要成果:
- 与单独使用PRF组相比,在PRF+SIM和PRF+MO组中观察到脊柱骨损失的减少.
- 当与PRF相结合时,simvastatin和Moringa oleifera都显示出对保护植入物周围的骨有有益影响.
- CBCT分析证实了治疗组的骨质再吸收减少.
结论:
- 将PRF支架与simvastatin和Moringa oleifera等骨质促进剂相结合,可以有效地减少牙科植入物周围的骨损失.
- 草药骨质促进剂在牙科植入学中显示出作为PRF的辅助剂的希望.
- 这些发现支持使用天然和合成骨质促进剂来改善牙科植入物周围骨再生的结果.
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