在过去的14年里,根据气候和墨西哥的皮肤测试气体过敏剂敏感度的变化
Désirée Larenas-Linnemann1, Blanca María Morfín-Maciel2, Victor Gonzalez-Uribe3
1Centro de Excelencia en Asma y Alergia Larenas, Hospital Médica Sur, Mexico City, DF, Mexico.
Journal of asthma and allergy
|August 12, 2024
概括
墨西哥14年来过敏原敏感性增加了,湿度影响了模式. 将目前的皮肤刺伤测试 (SPT) 结果与2009年数据进行比较,显示了呼吸道过敏触发因子的显著变化.
科学领域:
- 过敏和免疫学 过敏和免疫学
- 环境健康 环境健康
- 流行病学 流行病学
背景情况:
- 气体过敏原的暴露因地理位置和季节性而异,影响呼吸道过敏的流行率.
- 墨西哥多样化的气候需要了解区域气体过敏原敏感性模式.
- 2009年之前的研究强调了特定的敏感化趋势,为比较提供了基线.
研究的目的:
- 为了比较当前的空气过敏原敏感化模式与墨西哥14年前的模式.
- 分析墨西哥潮湿和干燥气候区之间的敏感度差异.
- 随着时间的推移,确定皮肤刺伤测试 (SPT) 对呼吸道过敏的阳性趋势.
主要方法:
- 在墨西哥19个城市的28个诊所收集了2915个皮肤刺探测试 (SPT) 的数据.
- 诊所被分为 (半) 湿和 (半) 干区域进行比较分析.
- 结果与2009年的一项研究进行了比较,统计分析包括赔率比率 (OR) 和95%置信区间 (95%CI).
主要成果:
- 在2009年至2023年期间 (OR 1.26-2.65) 观察到室内和室外空气过敏原的SPT阳性显著增加.
- 对Oleaceae,Fagaceae花粉,大多数杂草,Dermatophagoides和的敏感性在潮湿的地区更频繁.
- 对,梅花和草花粉的敏感性在干旱地区占主导地位,对猫或狗的过敏原没有显著差异.
结论:
- 在过去的14年中,SPT敏感度的普遍上升表明了除了气候变化之外的因素.
- 湿度是墨西哥地区空气过敏原敏感性概况的主要决定因素.
- 纵向流行病学SPT研究对于监测不断变化的过敏原敏感化趋势至关重要.
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