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避免/限制性食物摄入障碍的特征和发病率在成人乳病患者
Audrey Bennett1, Alexandra Bery2, Patricia Esposito1
1Department of Gastroenterology, Hepatology, and Nutrition, Vanderbilt University Medical Center, Nashville, Tennessee.
Gastro hep advances
|August 12, 2024
概括
避免/限制性食物摄入障碍 (ARFID) 常见于腹腔疾病 (CD) 患者. ARFID没有影响疾病控制或代谢并发症,但显著影响了生活质量.
科学领域:
- 胃肠病学 胃肠病学
- 精神病学是一个精神病学.
- 营养科学 营养科学
背景情况:
- 病 (CD) 是一种自身免疫性疾病,由摄入质引发.
- 患有CD的患者通常会出现胃肠道症状,并可能出现饮食挑战.
- 避免/限制性食物摄入障碍 (ARFID) 是一种以避免或限制食物摄入为特征的食障碍.
研究的目的:
- 为了确定ARFID在被诊断为患有乳病的成年患者中的患病率.
- 评估ARFID与代谢并发症,腹腔疾病控制和坚持无质饮食之间的关系.
- 评估ARFID,症状严重程度和CD患者的生活质量指标之间的相关性.
主要方法:
- 进行了一项回顾性研究,涉及137名患有CD的成年患者.
- 患者在2018年至2020年期间完成了CD诊所内的ARFID调查.
- 分析的数据包括人口统计,临床结果,饮食评估,症状日记和生活质量调查问卷.
主要成果:
- 超过一半 (57%) 的患者对疑似ARFID的查呈阳性.
- 在ARFID和非ARFID组之间,在年龄,性别,BMI,微量营养素缺乏或骨病方面没有发现显著差异.
- 与没有ARFID的患者相比,ARFID的患者在活检确认的乳活动或无质饮食坚持方面没有差异.
- 在"无质饮食问卷的影响"中报告的食物和社会负担是ARFID最强的预测因素.
结论:
- ARFID在乳病患者中非常普遍,并对他们的生活质量产生重大影响.
- 在CD患者中ARFID的存在似乎不必保持疾病控制.
- 虽然在这项为期2年的研究中代谢并发症并没有增加,但需要进一步的研究来了解ARFID在CD的长期影响和社会影响.
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