深静脉血栓瘤机械血栓切除术后的一年临床结果:一个简单的注册表分析
Mohannad B Bisharat1, Eugene J Ichinose2, Kalyan K Veerina3
1HCA Florida Memorial Hospital, Jacksonville, Florida.
概括
使用ClotTriever系统的机械血栓切除术显示,对深静脉血栓的1年结果有希望,血栓后综合征的发病率低,生活质量改善.
科学领域:
- 血管医学 血管医学
- 干预心脏病学 干预心脏病学
- 医疗器械 医疗器械
背景情况:
- 机械血栓切除术是一种新兴的深静脉血栓症 (DVT) 治疗方法.
- 对DVT机械血栓切除术的长期临床数据有限.
- 克洛特里弗结果 (CLOUT) 登记册评估了克洛特里弗系统的DVT治疗.
研究的目的:
- 评估机械血栓切除术对近端下肢深静脉血栓的1年临床结果.
- 评估血栓后综合征 (PTS) 发生率,静脉通透性和治疗后的生活质量 (QoL).
主要方法:
- 未来的,多中心的,单臂研究 (CLOUT注册,NCT03575364).
- 招募了500名患有近端下肢DVT的患者.
- 评估了1年的结果,包括Villalta得分,双重超声检查通透度,修订的静脉临床严重性得分和QoL.
主要成果:
- 19.3%的患者在1年后出现了血栓后综合征 (Villalta分数≥5).
- 在94.2%的受治疗四肢中观察到静脉通透性.
- 在Villalta得分,修订的静脉临床严重性得分和QoL中报告了显著的改善.
结论:
- 使用ClotTriever系统的机械血栓切除术显示了对DVT的一年有利的结果.
- 观察到血栓后综合征的低发病率和维护静脉通透性的情况.
- 改善的症状严重程度和生活质量表明这种治疗方法的有效性.
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