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Updated: Jun 17, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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双二环基构建块的平行最小反应

Serhii Holovach1,2, Illia Poroshyn1,3, Kostiantyn P Melnykov1,3

  • 1Enamine Ltd., Winston Churchill Street 78, Kyïv 02094, Ukraine.

ACS organic & inorganic Au
|August 12, 2024
PubMed
概括

碳酸在Minisci反应中与环基基构建块提供了比三基酸更好的产量. 异环核和CF2组显著影响循环基碎片的结合.

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