伊贝罗加斯特 (Iberogast®) 诱导的急性肝损伤-一个病例报告
Alice Leroy1, Henri Perrin1, Raphael Porret1
1Service de Médecine interne, CHUV, Lausanne, Switzerland.
Gastro hep advances
|August 12, 2024
概括
伊贝罗加斯特 (Iberogast®) 是一种流行的草药,很少会导致药物诱导的肝损伤. 医疗保健提供者应考虑在病史中使用草药产品,以有效诊断急性肝损伤.
科学领域:
- 综合医学是一个整体的医学.
- 肝病学 肝病学是一种肝病学.
- 药物监督 药物监督 药物监督
背景情况:
- 植物疗法和草药制剂被广泛使用,但在西方医学中经常被忽视.
- Iberogast®是一种常见的欧洲草药配方,含有Greater Celandine,用于功能性消化不良和刺激性肠综合征.
- 虽然通常是安全的,但报告了与Iberogast®相关的罕见不良事件.
研究的目的:
- 报告可能与Iberogast®使用相关的急性肝损伤病例.
- 强调在药物诱导的肝损伤的差异诊断中考虑草药药物的重要性.
- 强调需要全面的病史,包括植物疗法产品.
主要方法:
- 一个32岁的女性呈现急性严重肝炎症状的病例报告.
- 排除急性肝损伤的其他常见病因.
- 临床评估和实验室测试,包括直接胆红素水平.
主要成果:
- 患者出现了腹部疼痛,黄和,表明急性严重肝炎.
- 在排除其他原因后,诊断出与Iberogast®相关的药物诱导性肝损伤.
- 在停止Iberogast®后的5周内,症状自发消失.
结论:
- 偶尔出现药物诱导的肝损伤,即使使用一般安全的草药产品,如Iberogast®.
- 在病史中,应该经常询问草药和植物治疗产品的使用情况,以帮助诊断急性肝损伤.
- 这一案例强调了替代药物在理解药物不良反应方面的潜在相关性.
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