在化左侧冠状动脉主冠状动脉皮肤冠状动脉干预期间使用血管内溶液的回顾性多中心分析
Robert F Riley1, Larry E Miller2, Rhian Davies3
1Overlake Medical Center and Clinics, Bellevue, Washington.
概括
静脉内溶解 (IVL) 在皮肤冠状动脉干预 (PCI) 期间有效治疗化左主冠状动脉 (LMCA) 疾病,显示出高的成功和安全性. 这种方法有利于挑战LMCA病变.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 医疗器械 医疗器械
背景情况:
- 血管内透症 (IVL) 已被确立为结石化冠状动脉病变.
- 有限的数据存在于IVL对化左主冠状动脉 (LMCA) 疾病.
- 在皮肤冠状动脉干预 (PCI) 中,LMCA 疾病带来了独特的挑战.
研究的目的:
- 评估IVL辅助PCI在患有化LMCA疾病的患者的短期结果.
- 评估IVL在这个特定患者群体中的安全性和技术成功.
- 为了确定IVL辅助LMCAPCI后不良事件的预测因素.
主要方法:
- 在7个中心 (2019-2023) 进行IVL辅助PCI治疗化LMCA疾病的184名患者的回顾性分析.
- 血管内成像指导了这些程序.
- 技术成功定义为支架部署与<30%的残留狭窄;30天重大心脏不良事件 (MACE) 评估.
主要成果:
- 在IVL辅助的LMCA PCI中,技术成功率高达99.4%.
- 在IVL后82.4%的病例中观察到骨折.
- 显著增加最小光面积和IVL气球大小与最终最小支架面积 (MSA) 之间的相关性.
- 在住院的MACE为4.4%,30天的MACE为8.8%.
结论:
- IVL辅助的PCI是一种安全有效的治疗化LMCA病变的方法.
- 该程序在这个具有挑战性的子集中显示出高的技术成功率.
- 热波阳性心肌梗塞呈现是30天MACE的唯一预测因素.
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