在Cocculus hirsutus的叶子中的粘液的表征和抗氧化作用
Devasahayam Leema Rose Mary1, Antonysamy Lawrance1, Arokiadoss Edwina Sherley Felicita1
1PG & Research Department of Biochemistry, St. Joseph's College of Arts & Science (Autonomous), Cuddalore - 607001, Tamil Nadu, India.
Bioinformation
|August 12, 2024
概括
来自Cocculus hirsutus叶的粘液显示出有前途的植物化学和抗氧化特性. 这种可生物降解的天然聚合物是非细胞毒性的,这表明生物医学和药物输送应用的潜力.
科学领域:
- 生物化学 生物化学
- 材料科学 材料科学 材料科学
- 药理学 药理学是指药理学的学科.
背景情况:
- 天然多糖为生物医学用途提供可生物降解的替代品.
- 植物性粘液是有前途的候选物,因为它具有独特的特性.
- 科科 (Cocculus hirsutus mucilage) 的生物医学潜力尚未得到广泛研究.
研究的目的:
- 从Cocculus hirsutus叶子中分离和描述粘液.
- 评估其植物化学成分,物理化学性质和结构特征.
- 评估其抗氧化能力和体外细胞毒性.
主要方法:
- 从Cocculus hirsutus的叶子中分离出来的化物.
- 植物化学查,溶解度,pH值和胀指数的确定.
- 福利埃变换红外光谱法 (FTIR),气色谱法-质谱法 (GC-MS) 和扫描电子显微镜 (SEM) 分析.
- 对抗氧化活性进行DPPH,FRAP和总还原功率测定.
- 在体外细胞毒性测定使用纤维细胞细胞系.
主要成果:
- 化率为26%,胀指数为6.8 - 7.4.4.
- 植物化学分析揭示了碳水化合物,黄类,类,类,桑类,沙类,糖化物和类固醇.
- FTIR证实了主要的功能组,SEM显示了多孔表面形态.
- 在DPPH,FRAP和降低功率测试中观察到显著的抗氧化剂潜力.
- 粘液在纤维细胞细胞系上表现出非细胞毒性作用.
结论:
- 科科 (Cocculus hirsutus) 粘液具有丰富的植物化学特征和显著的抗氧化活性.
- 它的多孔结构和非细胞毒性使其适用于各种生物应用.
- 这种天然聚合物有可能用于食品,化品和药物输送系统.
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