运动体形对成像策略的影响在人体内皮层内大脑与计算机接口的成功
N G Kunigk1,2,3, H R Schone1,4, C Gontier1,4
1Rehab Neural Engineering Labs, University of Pittsburgh, Pittsburgh, PA, USA.
medRxiv : the preprint server for health sciences
|August 12, 2024
概括
电极在运动皮层中的放置会影响大脑与计算机接口的控制. 介面阵列更好地捕捉近端手臂运动,而侧面阵列在远端运动中表现出色,影响解码精度.
科学领域:
- 神经科学是一个神经科学.
- 生物医学工程 生物医学工程
- 康复医学 康复医学 康复医学
背景情况:
- 运动皮层传统上被认为是体形组织的,有不同的区域控制特定的身体部位.
- 最近的研究表明,运动控制的神经表现更加分布.
- 了解这种组织对于优化皮质内脑计算机接口 (iBCI) 至关重要.
研究的目的:
- 为了研究电极阵列位置在前中心环内对神经记录和iBCI控制的影响.
- 为了确定体内形状是否影响不同神经解码策略的有效性.
主要方法:
- 从三名脊髓损伤患者的前中心环中植入的皮质内微电极阵列记录的神经数据.
- 在尝试手,手腕,肘部和肩部运动时分析神经活动.
- 根据不同的图像策略,评估每个数组对解码精度的贡献.
主要成果:
- 与侧向电极阵列相比,中间电极阵列在近接手臂运动 (肘部,肩膀) 中表现出更高的活动.
- 侧向阵列捕获了更多与远端手臂运动 (手,手腕) 相关的活动.
- 图像策略显著影响了每个数组对解码精度的相对贡献.
结论:
- 运动皮层中的体质造影对iBCI性能有明显的影响.
- 空间上不同的皮质区域显示出不同运动类型的信息内容的偏差.
- 在iBCI植入规划期间考虑体质学是最大限度地提高控制能力的必要条件.
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