在大的巨细胞病变中,单核细胞细胞形成
Sebastião Silvério Sousa-Neto, Gimenna Barbosa Pereira, Elismauro Francisco Mendonça
1Universidade Evangélica de Goiás, Department of Oral Diagnosis, Avenida Universitária, Km 3, 5, s/n, Cidade Universitária, Anápolis, Goiás, Brazil. ZIP-code: 75083-515. allissonfilipe@hotmail.com.
Stomatologija
|August 12, 2024
概括
多核巨细胞中细胞发生的事件可能表明中央巨细胞病变 (CGCL) 的攻击性. 攻击性CGCL和外围巨细胞病变 (PGCL) 与非攻击性CGCL相比,表现出更高的细胞化.
科学领域:
- 口腔病理学 口腔病理学
- 在瘤学瘤学.
- 细胞生物学 细胞生物学
背景情况:
- 中央巨细胞病变 (CGCL) 是一种良性骨内病变.
- CGCL可以是侵略性的或非侵略性的,缺乏明确的行为生物标志物.
- 干细胞细胞症是侵略性病变的潜在标志物,但在CGCL中没有充分研究.
研究的目的:
- 为了比较由多核巨细胞对单核细胞的细胞.
- 要区分攻击性,非攻击性CGCL和外围巨细胞病变 (PGCL).
主要方法:
- 对33例CGCL (10例侵略性,23例非侵略性) 和20例PGCL病例进行了组织学分析.
- 对每平方毫米的细胞发生事件的量化,与多核巨细胞相关.
- 血素和欧染色用于显微镜评估.
主要成果:
- 在所有评估的多核巨细胞中都存在着细胞.
- 与PGCL相比,在CGCL中观察到更高的吞细胞密度.
- 具有侵略性的CGCL比非具有侵略性的CGCL表现出显著更多的细胞发生事件.
结论:
- 细胞发生事件的数量可能与中的多核巨细胞病变的攻击性有关.
- 细胞形成可以作为评估CGCL行为的潜在生物标志物.
相关概念视频
Phagocytosis
6.3K
Cells pull particles inward and engulf them in spherical vesicles in an energy-requiring process called endocytosis. Phagocytosis ("cellular eating") is one of three major types of endocytosis. Cells use phagocytosis to take in large objects, such as other cells (or their debris), bacteria, and even viruses.
The objective of phagocytosis is often destruction. Cells use phagocytosis to eliminate unwelcome visitors, like pathogens (e.g., viruses and bacteria). Many immune system cells,...
The objective of phagocytosis is often destruction. Cells use phagocytosis to eliminate unwelcome visitors, like pathogens (e.g., viruses and bacteria). Many immune system cells,...
6.3K
Immune Surveillance by NK Cells and Phagocytes
1.4K
Immune surveillance is an integral part of the innate immune system, involving the continuous monitoring of peripheral tissues to detect and respond to pathogens, infected cells, or cancerous cells. This surveillance is conducted primarily by natural killer (NK) cells and phagocytes, which employ distinct but complementary mechanisms to identify and eliminate threats.
Natural Killer Cells: The Fast Responders
NK cells are large granular lymphocytes found in the blood and lymphatic system. These...
Natural Killer Cells: The Fast Responders
NK cells are large granular lymphocytes found in the blood and lymphatic system. These...
1.4K
Phagocytosis of Apoptotic Cells
3.7K
Cells undergoing apoptosis form apoptotic bodies that must be removed immediately to prevent inflammation, autoimmune diseases, and necrosis. Phagocytosis is carried out by professional phagocytes such as macrophages or immature dendritic cells. Non-professional phagocytes such as epithelial cells and fibroblasts also take part in this process; however, they are not as effective as professional phagocytes.
Normal cells contain receptors that prevent them from being recognized...
Normal cells contain receptors that prevent them from being recognized...
3.7K
Cells of the Innate Immune Response
1.6K
The innate immune response is an immediate and non-specific response against pathogens, acting swiftly to prevent the spread of infections. The primary cells involved in this response are phagocytes and natural killer (NK) cells.
Phagocytes
Phagocytes police the peripheral tissues by removing cellular debris and responding to the invasion of foreign substances or pathogens. Many phagocytes attack and remove microorganisms even before lymphocytes detect them. The human body has two general...
Phagocytes
Phagocytes police the peripheral tissues by removing cellular debris and responding to the invasion of foreign substances or pathogens. Many phagocytes attack and remove microorganisms even before lymphocytes detect them. The human body has two general...
1.6K
Classification of Leukocytes
1.8K
Leukocytes are classified into two groups based on the presence or absence of cytoplasmic granules. Granular leukocytes, which contain granules, belong to the myeloid lineage and are divided into three subtypes: neutrophils, eosinophils, and basophils. These cells are roughly spherical and characterized by the granules in their cytoplasm.
Neutrophils are the most abundant type of granular leukocytes, comprising 50-70% of all leukocytes. They feature small, evenly distributed granules and a...
Neutrophils are the most abundant type of granular leukocytes, comprising 50-70% of all leukocytes. They feature small, evenly distributed granules and a...
1.8K


