在瑞典中年人口中,与吸烟习惯相关的慢性空气流量限制,肺气和扩散能力受损在瑞典中年人口中
Anders Blomberg1, Kjell Torén2,3, Per Liv1
1Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
慢性气流限制 (CAL) 和肺扩散能力受损 (DlCO) 在中年成人中很常见,并与呼吸系统症状有关. 从未吸烟者中的CAL可能代表一个不同的临床群体,需要量身定制的管理.
科学领域:
- 肺部医学 肺部医学
- 流行病学 流行病学
- 放射学 放射学是一门学科.
背景情况:
- 慢性阻塞性肺病 (COPD) 包括呼吸系统症状和慢性空气流限制 (CAL).
- 肺气和肺部对一氧化碳 (DlCO) 的扩散能力受损可能存在,因吸烟史而有变化.
- 了解与吸烟和症状相关的CAL,肺气和受损DlCO的患病率对于公共卫生至关重要.
研究的目的:
- 为了确定中年人口中CAL,肺气和DlCO受损的患病率.
- 调查这些肺部疾病,吸烟状况和呼吸系统症状之间的联系.
- 探索从未吸烟者中CAL的特征.
主要方法:
- 一项基于人口的研究,涉及6个瑞典地点的28746名年龄在50-64岁的人.
- 进行了螺旋测量,DlCO测试和高分辨率计算机断层扫描.
- 收集了关于吸烟习惯和呼吸系统症状的数据;CAL被定义为FEV1/FVC < 0.7.7.
主要成果:
- 总体患病率:CAL为8.8%,DLCO受损为5.7%,肺气为8.8%.
- 与前吸烟者和从未吸烟者相比,目前吸烟者中观察到这些疾病的患病率更高.
- 在CAL和DlCO受损患者中,呼吸道症状更频繁,不论吸烟习惯如何.
结论:
- CAL和受损的DlCO与中年成人常见的呼吸道症状有关.
- 在从未吸烟者中,喘与CAL无关,这表明有不同的临床表型.
- 与吸烟相关的COPD相比,从不吸烟者的CAL可能需要单独的监测和治疗策略.
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