妇女怀孕与丰坦循环:短期和长期的结果
Susanna Breviario1, Kaushiga Krishnathasan2, Konstantinos Dimopoulos2
1Adult Congenital Heart Centre and Centre for Pulmonary Hypertension, Royal Brompton Hospital, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
International journal of cardiology
|August 12, 2024
概括
患有芬坦循环的妇女怀孕与高早产率和新生儿并发症有关,但母亲心脏事件很少发生. 中期结果通常是积极的,尽管长期生存影响尚不清楚.
科学领域:
- 心脏病学 心脏病学
- 生殖医学 生殖医学
- 儿科 儿科 儿科
背景情况:
- 护理方面的进步使得单心室生理学的妇女能够达到生育年龄.
- 喷泉循环是单心室生理学的标准息手术.
研究的目的:
- 为了检查怀孕对Fontan循环妇女的影响.
- 评估Fontan循环的孕妇的短期和长期结果.
主要方法:
- 在妇女怀孕的回顾性分析与Fontan循环 (2005-2023).
- 包括一个匹配的非怀孕的,无双的队列进行比较.
- 在怀孕18周之前失去了怀孕的单独分析.
主要成果:
- 18名妇女的26次怀孕导致73.1%的早产,3个胎儿丧生,没有母亲死亡.
- 50%的新生儿对于妊娠年龄 (SGA) 是小的;19.2%的怀孕发生了心脏事件 (心室上节律失常).
- 23%经历了产后出血;中位数6.1年的随访没有显示死亡,心力衰竭 (HF) 或Fontan相关的肝病 (FALD).
结论:
- 患有丰坦血循环的妇女怀孕会有分娩后出血和新生儿并发症的风险,例如生长受限和早产.
- 发生的严重母亲心脏事件很少;中期前景一般是积极的.
- 仔细的怀孕前咨询对于患者选择以减轻风险至关重要.
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