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Updated: Jun 28, 2026

Preparation of Synaptoneurosomes from Mouse Cortex using a Discontinuous Percoll-Sucrose Density Gradient
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Published on: September 17, 2011

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在小鼠大脑中的突触蛋白循环的形态相关物

Fengxia Li1,2, Julius N Bahr2,3,4, Felicitas A-L Bierth2,3,5

  • 1Department of Neuro- and Sensory Physiology, University Medical Center Göttingen, Göttingen, Germany.

Life science alliance
|August 12, 2024
PubMed
概括

突触蛋白的循环,对于大脑功能至关重要,反映在突触结构. 年龄较大的小鼠表现出减少的周转率和改变的形态,表明与年龄相关的突触维护变化.

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相关概念视频

Protein-protein Interfaces02:04

Protein-protein Interfaces

Many proteins form complexes to carry out their functions, making protein-protein interactions (PPIs) essential for an organism's survival. Most PPIs are stabilized by numerous weak noncovalent chemical forces. The physical shape of the interfaces determines the way two proteins interact. Many globular proteins have closely-matching shapes on their surfaces, which form a large number of weak bonds. Additionally, many PPIs occur between two helices or between a surface cleft and a polypeptide...