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Updated: Apr 11, 2026

gDNA Enrichment by a Transposase-based Technology for NGS Analysis of the Whole Sequence of BRCA1, BRCA2, and 9 Genes Involved in DNA Damage Repair
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在干燥的pBR322等离子体中对剂量依赖DNA碎片化的定量分析,使用长读数测序和蒙特卡洛模拟

Pierre Beaudier1,2, Sara A Zein1, Konstantinos Chatzipapas1

  • 1CNRS, LP2iB, UMR 5797, Univ. Bordeaux, 33170, Gradignan, France.

Scientific reports
|August 12, 2024
PubMed
概括

电离辐射会导致DNA受损. 长读测序揭示了剂量依赖的DNA碎片化和测量单链断裂的新方法,推进了辐射损伤研究.

关键词:
损伤的DNA会导致DNA受损.电离辐射辐射的电离辐射.蒙特卡洛模拟的蒙特卡洛模拟纳米孔测序的测序

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相关概念视频

Maxam-Gilbert Sequencing01:05

Maxam-Gilbert Sequencing

In the same year as the discovery of the Sanger sequencing method, another group of scientists, Allan Maxam and Walter Gilbert, demonstrated their chemical-cleavage method for DNA sequencing. The Maxam-Gilbert method relies on using different chemicals that can cleave the DNA sequence at specific sites, the separation of resulting DNA fragments of variable size using electrophoresis, and deciphering the DNA sequence from the resulting gel bands.
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