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Updated: Jun 17, 2025

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通过诱导HDAC6,SARS-CoV-2核体蛋白促进自我脱乙烯化,以促进病毒复制

Arpita Mukherjee1, Mahadeb Lo1, Pritam Chandra1

  • 1Division of Virology, ICMR-National Institute of Cholera and Enteric Diseases, P-33, C.I.T. Road, Scheme-XM, Beliaghata, Kolkata, West Bengal, 700010, India.

Virology journal
|August 12, 2024
PubMed
概括

海斯脱乙酶6 (HDAC6) 通过脱乙病毒N蛋白来促进SARS-CoV-2的复制,从而破坏压力颗粒. 抑制HDAC6可以降低病毒载量,这表明它是抗病毒点.

关键词:
脱乙化 脱乙化 脱乙化在 G3BP1 中使用.在 HDAC6 中.这就是SARS-CoV-2病毒.应力颗粒 (SG) 是一种压力颗粒.

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