2023年ACR/EULAR抗脂综合征分类标准的制定,III-D期报告:多标准决策分析
Medha Barbhaiya1, Stephane Zuily2, Mary-Carmen Amigo3
1Hospital for Special Surgery, Weill Cornell Medicine, New York City, New York.
Arthritis care & research
|August 13, 2024
概括
2023年美国风湿病学院/EULAR抗脂综合征 (APS) 标准使用多标准决策分析 (MCDA) 权衡候选因素. 为APS分类建立了单独的临床和实验室领域值,增强了特异性.
科学领域:
- 类风湿病学 类风湿病学
- 临床免疫学临床免疫学
- 医学分类系统 医学分类系统
背景情况:
- 美国风湿学会/EULAR2023年抗脂综合征 (APS) 分类标准是为研究目的而开发的,旨在识别患有APS高概率的患者.
- 之前的阶段 (I和II) 产生了27个候选标准,分为实验室和临床领域.
研究的目的:
- 总结一下APS分类标准开发的最后阶段 (第三阶段).
- 采用基于共识的多标准决策分析 (MCDA) 来确定候选标准的相对权重.
- 为确定分类APS患者的值得分.
主要方法:
- 对192名国际患者的评估,涉嫌有APS和各种表现.
- 小组委员会成员对20名代表性患者进行了排名,并改进了候选人标准的定义.
- 在使用1000Minds软件的MCDA练习中,基于共识决策和对对比,分配了权重.
- 患者使用附加分数进行排名,并设置了一个共识值.
主要成果:
- 初步评估显示,小组委员会成员在APS评估中存在差异.
- 在MCDA的帮助下,我们做出了81个双向决策,建立了域项的层次结构.
- 指导委员会确定,单独的临床和实验室得分,而不是单一的总得分,对于APS分类的高特异性是必要的.
结论:
- 候选APS分类标准的初步权重是使用MCDA确定的.
- 新的APS分类标准独特地包含了临床和实验室领域的单独门,与单个总分数系统不同.
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