在ICU患者的连续脏替代疗法的意外断奶的危险因素:一个元分析
Zhi Zeng1, Yuqi Shen1, Li Wan1
1Intensive Care Unit, Mianyang Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Mianyang, Sichuan Province, China.
Renal failure
|August 13, 2024
概括
在ICU患者的连续脏替代疗法 (CRRT) 意外断奶与低血压,低温,老年和缺乏专注护理等因素有关. 早期识别这些风险因素对于预防至关重要.
科学领域:
- 临界护理医学 临界护理医学
- 腎臟病學 (nephrology) 是一種醫學專業.
- 重症监护病房 (ICU) 管理管理
背景情况:
- 连续置换疗法 (CRRT) 是严重功能障碍患者的重要治疗方法.
- 意外的中断或从CRRT中断可以导致患者的不良结果.
- 识别非计划性CRRT断奶的风险因素对于改善ICU患者护理至关重要.
研究的目的:
- 在ICU患者的CRRT期间系统审查和元分析与非计划断奶相关的风险因素.
- 为制定预防CRRT中断策略提供基于证据的见解.
主要方法:
- 在多个数据库 (PubMed, EMbase, Web of Science等) 进行了全面的文献搜索. 在2024年6月25日之前.
- 用Revman 5.4和Stata15.0软件确定了非计划性CRRT断奶的风险因素,并进行了元分析.
- 该分析包括23项研究,包括3793名患者和7197个过器.
主要成果:
- 无计划CRRT断奶的重大风险因素包括平均低血压,低温,年龄较大 (≥60岁),并发性疾病和激动.
- 其他已识别的危险因素包括不使用抗凝剂,短激活部分原血时间,高血红素,低电离,高剂量CRRT,机械通风和缺乏专注的护理.
- 血小板计数,前列血活性和血液流速的作用需要进一步调查.
结论:
- 在ICU患者中,多种因素导致非计划的CRRT断奶.
- 这些已识别的风险因素的早期识别和管理对于医疗保健专业人员来说至关重要.
- 实施预防和治疗策略可以帮助减少计划外的CRRT中断,并改善患者的治疗结果.
相关概念视频
Renal Failure: Dose Adjustments
77
In patients with renal impairment, drugs undergo significant changes in their pharmacokinetics, which require dosage adjustments to ensure safe and effective therapy.
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
77
Factors Affecting Renal Clearance: Renal Impairment
68
Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
68
Endotracheal Tube Extubation
516
Endotracheal tube extubation is a critical procedure in weaning patients from mechanical ventilation. It involves physically removing the oral or nasal endotracheal (ET) tube, marking the final step in liberating a patient from ventilatory support.
Procedure
Extubation removes the endotracheal tube (ETT) from the patient on mechanical ventilation. It requires a well-coordinated, multidisciplinary approach involving physicians, nurses, respiratory therapists, and other healthcare professionals....
Procedure
Extubation removes the endotracheal tube (ETT) from the patient on mechanical ventilation. It requires a well-coordinated, multidisciplinary approach involving physicians, nurses, respiratory therapists, and other healthcare professionals....
516
Dialysis
281
Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
281
Parentral Nutrition: Centeral and Peripheral Parental Nutrition
115
Parenteral Nutrition (PN) delivers essential nutrients directly into the bloodstream, bypassing the digestive system. It is commonly used for individuals with severe digestive disorders or conditions that prevent normal nutrient absorption.
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
115
Acute Respiratory Failure-V
126
The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Ensure that patients are monitored continuously for their response to therapy, including changes in...
126


