日本严重喘患者的流行病学:全国性的描述性研究
Yuya Kimura1,2, Maho Suzukawa2, Taisuke Jo3,4
1Department of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, Tokyo, Japan.
ERJ open research
|August 13, 2024
概括
在过去的十年中,日本严重喘的患病率有所下降,下降到5%以下. 尽管喘治疗方面取得了进展,但许多患者仍然出现无法控制的症状.
科学领域:
- 肺部病理学 肺部病理学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 2014年欧洲呼吸学会/美国胸腔学会的指导方针定义了严重喘,但缺乏关于其患病率的全面数据.
- 据估计,严重喘占所有喘病例的5-10%,因此需要更新流行病学数据.
研究的目的:
- 在过去十年中,估计日本严重喘的全国患病率和比例.
- 分析喘患者的人口特征,治疗方法和结果.
主要方法:
- 利用日本国家行政数据库,覆盖99%以上的人口.
- 评估了2013年,2015年,2017年和2019年的严重喘患病率和比例.
主要成果:
- 2019年,严重喘患病率为每10万人中有36人,比前几年下降,导致4.3%的比例.
- 尽管生物药物等治疗方法不断发展,但大约45%的严重喘病例仍未得到控制.
- 在轻度中度和重度喘类别中,喘相关死亡人数下降.
结论:
- 日本的严重喘患病率已经下降,低于此前估计的5%.
- 轻度中度和重度喘患者中的很大一部分继续经历症状控制不良.
- 进一步研究优化喘管理策略是有必要的.
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