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过渡性变化不匹配的消极性在两次电治疗异型精神病的会议后:一个案例报告

Yuhei Mori¹, Kazuko Kanno¹, Hiroshi Hoshino¹

¹Department of Neuropsychiatry, School of Medicine Fukushima Medical University Fukushima Japan.

PCN reports : psychiatry and clinical neurosciences

|August 13, 2024

概括

电疗法 (ECT) 可以导致暂时的认知变化,如延迟的不匹配负面性 (MMN) 反应和治疗后较低的认知分数所示. 这些影响在40天内消失,表明过渡性认知异常.

科学领域:

神经科学是一个神经科学.
精神病学是一个精神病学.

背景情况:

认知异常是电治疗 (ECT) 的已知副作用之一.
不匹配负面性 (MMN) 是一种听觉变化检测的电生理学测量,对精神障碍中的认知功能敏感.
这项研究调查了MMN和认知功能变化后ECT在一个患有非典型精神病的患者.

研究的目的:

为了研究两次ECT治疗后MMN和认知功能的变化.
评估维护ECT对非典型精神病患者听觉处理的影响.

主要方法:

一个案例研究涉及一个67岁的女性患者,患有非典型精神病,正在接受维护ECT.
测量持续时间-MMN (MMN-D) 在基线,两个ECT会话后立即,大约40天后.
使用精神分裂症认知简要评估 (BACS) 评估的认知功能在同一时间点.

主要成果:

在ECT后的第二天观察到MMN峰值延迟,表明过渡性认知异常.
在ECT后大约40天,MMN峰值延迟恢复到基线水平.
在ECT后,BACS得分显示出类似的暂时下降,反映了MMN的发现.

结论:

延长MMN峰值延迟表明过渡性认知功能障碍是ECT的不良影响.
MMN可以作为评估ECT诱导认知障碍的潜在工具.
需要进一步的研究来确认可复制性,并在其他条件下探索MMN.

关键词:

非典型的精神病症.电疗法是一种电疗法.与事件相关的潜在事件.不匹配的消极性,消极的消极性

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Electroconvulsive Therapy

Electroconvulsive Therapy

Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...