基于问卷的体力活动分析与2型糖尿病的身体组成动态的结合:一项跨部门研究
Dan-Dan Li1, Xue Yang1, Yang Yang2
1Department of Endocrinology, Affiliated Hospital 2 of Nantong University, and First People's Hospital of Nantong City, Nantong, 226006, People's Republic of China.
Diabetes, metabolic syndrome and obesity : targets and therapy
|August 13, 2024
概括
2型糖尿病患者的低体力活动与较差的身体组成有关. 活动减少独立增加脂肪,减少骨密度和肌肉质量.
科学领域:
- 内分泌学 在内分泌学.
- 代谢健康 代谢健康
- 运动生理学 运动生理学
背景情况:
- 身体活动 (PA) 在2型糖尿病 (T2D) 中显著影响血糖控制.
- 在T2D患者中,PA和身体组成变化的关系仍未得到充分研究.
- 身体组成的改变与T2D的病理生理学有关.
研究的目的:
- 调查T2D患者体育活动水平与身体组成之间的关联.
- 确定体力活动是否是T2D体质组成参数的独立预测因素.
- 分析骨矿物质密度,骨肌肉质量和脂肪含量相对于PA水平的变化.
主要方法:
- 615名T2D患者使用国际体力活动问卷 (IPAQ-S) 进行了评估.
- 使用双能X射线吸收计 (DXA) 评估身体组成,测量骨矿物质密度 (LSBMD, FNBMD, HBMD, TBMD),骨肌肉指数 (ASMI) 和脂肪百分比 (B-FAT, T-FAT).
- 患者被分为低,中,高体力活动组进行比较分析.
主要成果:
- 身体活动减少与HbA1c,体脂肪 (B-FAT,T-FAT) 和骨周转标记物 (β-CTX,TP1NP) 的增加相关.
- 较低的体力活动与骨矿物质密度 (LSBMD,FNBMD,HBMD,TBMD) 和骨肌肉指数 (ASMI) 的显著下降有关.
- 多重回归分析证实,身体活动水平独立预测T2D患者的骨密度,肌肉质量和脂肪含量.
结论:
- 缺乏体力活动是T2D中不利的身体组成变化的一个独立风险因素.
- 降低PA与骨矿物质密度和骨肌肉质量下降有关.
- 不活动会导致T2D患者脂肪积累增加.
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