与心肌梗塞相关的长非编码RNA的进展和趋势:一个文献测量分析
Qingkun Meng1, Hao Tan2, Chengfu Wang1
1Department of Cardiology, The People's Hospital of China Medical University, Shenyang, China.
Frontiers in molecular biosciences
|August 13, 2024
概括
在心肌梗塞 (MI) 中对长非编码RNA (lncRNAs) 的研究在全球范围内激增. 中国在出版物方面处于领先地位, lncRNAs显示出作为MI的治疗点的潜力.
科学领域:
- 心血管生物学 心血管生物学
- 分子遗传学 分子遗传学
- 生物医学研究生物医学研究
背景情况:
- 心肌梗塞 (MI) 显著影响患者的治疗结果和死亡率.
- 长非编码RNAs (lncRNAs) 越来越多地被认为在MI发育和进展中的关键作用.
- 了解MI相关 lncRNAs 的研究环境对于推进该领域至关重要.
研究的目的:
- 进行对与心肌梗塞相关的长非编码RNA研究的文献分析.
- 确定这一研究领域的关键趋势,有影响力的国家,机构和作者.
- 提供有关当前研究主题和MI-lncRNA研究未来方向的见解.
主要方法:
- 在Web of Science核心集合 (WoSCC) 数据库中进行了全面的文献搜索.
- 从1452个英语出版物 (2000年1月至2023年8月) 收集和分析了数据.
- 用CiteSpace,VOSviewer,一个在线平台和R-Studio.com进行了图书识别分析和可视化.
主要成果:
- 出版量呈指数级增长,2020年达到顶峰.
- 中国是最多产的国家,其次是美国.
- 关键的研究主题包括基因表达,动脉样硬化,亡以及心脏缺血/再损伤.
结论:
- 与心脏病相关的lncRNAs的研究迅速扩大,中国和美国的贡献很大.
- lncRNAs在心脏病发作中起着至关重要的作用,具有作为治疗点和生物标志物的潜力.
- 需要加强全球学术交流,以进一步推进这一研究领域.
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